The Apothecary Diaries has taken the anime world by storm with its rich historical setting, intricate court intrigue, and unforgettable cast of characters. From clever maids to cunning nobles, every character is layered with motivations, secrets, and distinctive traits. But fans may have wondered which character best matches their zodiac sign, and not based on their actual birthdays, but on personality and energy.

Zodiac signs offer a fascinating lens into personality types, from fiery Aries to grounded Capricorns and emotionally intuitive Pisceans. By analyzing the core traits of each sign, they can be matched with characters from The Apothecary Diaries who share similar drives, reactions, and quirks. So whether fans are a logical Virgo or a dramatic Leo, there is a character in the imperial palace that mirrors their cosmic identity.

12 Aries - Maomao

March 21 – April 19

Bold, independent, and often charging ahead without waiting for permission, Aries is the natural warrior of the zodiac, and Maomao is the perfect match. With a razor-sharp mind and a fearless attitude, Maomao dives headfirst into every mystery, illness, or palace plot without a second thought. Like a true Aries, she trusts her instincts over authority and often finds herself in hot water for refusing to stay silent or submissive. She is brash, witty, and never afraid to call out nonsense, even when it could cost her.

Much like Aries, Maomao thrives on challenge. She gets bored easily and seeks out stimulation, often in the form of obscure poisons or unraveling deadly secrets. Maomao is not content being a background character in her own life, and Aries signs will relate to that fierce desire to live boldly and solve problems in their own way. Her resilience and independence embody the Aries spirit, because she may stumble, but she never backs down.

11 Taurus - Gaoshun

April 20 – May 20

Taurus is known for its patience, reliability, and devotion, and no one in The Apothecary Diaries personifies that more than Gaoshun, the ever-loyal aide to Jinshi. Calm, composed, and always three steps ahead, Gaoshun has the aura of someone who knows how to endure. Tauruses are the rocks of the zodiac, and Gaoshun is exactly that to the emotionally mercurial Jinshi. He never panics, always listens, and manages complex situations with a quiet, commanding presence.

Beyond his cool demeanor lies the Taurus love for comfort and stability. He does not crave attention, but he deeply values order and harmony. His loyalty is not loud, but it is unwavering, and he will go to great lengths to protect those he serves. Like most Tauruses, he believes in actions over words. While others react in chaos, Gaoshun remains the dependable force that keeps the inner palace from tipping too far into disorder. He is the ultimate example of “slow and steady wins the race.”

10 Gemini - Suirei

May 21 – June 20

Witty, talkative, and intellectually curious, Geminis are the communicators of the zodiac, and Suirei fits this mold perfectly. A high-ranking court lady with a sharp tongue and a mind for manipulation, Suirei is always engaged in some subtle form of conversation or strategy. Geminis are often underestimated due to their flirtatious or flighty reputations, but underneath, they are highly observant and skilled in adapting to different social environments. Suirei’s ability to navigate palace politics with ease speaks to her Gemini nature.

What makes Suirei especially Gemini-like is her duality, because she can switch between sweet and cunning in an instant. She knows how to read a room and matches her tone to the moment. But behind that social charm lies a desire for knowledge and influence. Geminis hate stagnation, and Suirei always seeks to position herself advantageously, adjusting her words and alliances with effortless grace. If fans are a Gemini, they will appreciate her mental agility and restless curiosity.

9 Cancer - Xiaolan

June 21 – July 22

Cancers are deeply emotional, nurturing, and loyal, which are qualities that are important to Xiaolan’s personality. As one of Maomao’s closest friends in the palace, The Apothecary Diaries that often feels cold and treacherous. She is not loud or attention-seeking, but her presence is comforting and essential. Like most Cancers, she forms deep bonds and cares intensely for the people she trusts.

Cancers will connect with Xiaolan’s quiet strength and emotional loyalty, as well as her ability to provide calm in the storm.

However, Cancer’s emotional depth also makes them protective and sometimes hesitant to let people in. Xiaolan exhibits this in her cautious nature; she does not throw herself into danger the way Maomao does, but she s from the sidelines with genuine care. She values relationships over power and brings a humanizing softness to the harsh realities of palace life. Cancers will connect with Xiaolan’s quiet strength and emotional loyalty, as well as her ability to provide calm in the storm.

8 Leo - Jinshi

July 23 – August 22

Leos are charismatic, dramatic, and born to shine, just like Jinshi, the beautiful and mysterious official who turns heads everywhere he goes. Jinshi thrives in the spotlight, often manipulating it to his advantage. He knows how to command a room, whether by sheer attractiveness or by deploying his charm in strategic ways. Leos love being adored, and Jinshi’s outward persona is practically regal in how carefully he crafts his image.

Yet, as with many Leos, there’s more beneath the surface. Jinshi hides vulnerabilities and complexities behind his brilliance, and this duality defines him. He is not just a showman; he is fiercely protective of those he cares about, especially Maomao, and deeply committed to justice in his own way. Like any Leo, he seeks recognition, but not always for vanity. He wants to matter, to lead, and to make lasting change. Leos will see themselves in his pride, ion, and inner struggle to balance image with integrity.

7 Virgo - Lihaku

August 23 – September 22

Logical, responsible, and quietly ambitious, Lihaku is a classic Virgo through and through. A military officer with a sense of duty and a hidden romantic streak, Lihaku approaches everything with methodical care. Virgos are perfectionists by nature, and Lihaku shows this in how he handles his responsibilities, never slacking even when unnoticed. He is not flashy, but his competence speaks volumes, a trait any Virgo would ire.

Despite his reserved exterior, Lihaku has depth, just like Virgo, whose cool demeanor often hides sensitivity. He is observant and takes the time to understand others, even if he rarely voices his feelings. His affection for Pairin, though subtle, is deeply felt and thoughtfully expressed. Virgos will appreciate his grounded nature, his sense of duty, and his quiet desire to be useful and seen. He is the type who stands in the background until it really matters, and then he shines.

6 Libra - Lady Gyokuyou

September 23 – October 22

Graceful, diplomatic, and aesthetically inclined, Libras are born for elegance and balance, which are two words that define Lady Gyokuyou. As one of the imperial consorts, Gyokuyou carries herself with poise and beauty, but do not mistake her for just another pretty face. She understands the art of social harmony and wields her influence with both kindness and intelligence. Libras are known for their love of peace and fairness, and Gyokuyou’s sense of justice and empathy sets her apart.

At her core, Lady Gyokuyou is deeply people-oriented. She sees the value in relationships and often plays the role of peacemaker, even within the competitive, high-stakes world of the inner palace. Libras seek equilibrium in all things, and Gyokuyou manages to maintain her moral com without falling into naivety. She is both idealistic and strategic, just like many Libras who want to make the world better without creating too much discord in the process.

5 Scorpio - Luomen

October 23 – November 21

Scorpios are intense, mysterious, and always digging deeper, exactly like Luomen, Maomao’s adoptive father and an expert in both medicine and secrets. While he is not as flamboyant as some of the characters in The Apothecary Diaries, Luomen’s emotional depth and shocking intellect make him very much a Scorpio. He does not show his hand often, but when he does, it is with big impact. Scorpios value knowledge and power, and Luomen clearly possesses both.

What makes Luomen especially Scorpio-like is his relationship with Maomao. There is a deep undercurrent of emotion and loyalty, even if he expresses it in a stoic, hands-off way. Scorpios are also fiercely protective of their loved ones, often in hidden ways. Luomen’s past is shrouded in mystery, and his calm demeanor masks a storm of knowledge, intention, and unspoken affection. Scorpios will recognize his subtle intensity and his ability to command respect without ever raising his voice.

4 Sagittarius - Meimei

November 22 – December 21

Adventurous, blunt, and fiercely independent, Sagittarius finds its ideal counterpart in Meimei, the renowned courtesan from the pleasure district. With her unfiltered honesty and bold spirit, Meimei thrives outside the constraints of palace decorum and polite society. Sagittarians are known for their love of freedom, and Meimei lives unapologetically on her own . She has traveled through hardship and success alike, and much like the Sagittarius archer, she is always aiming for something higher, even if it means challenging societal norms.

There is also a philosophical bent to Meimei’s worldview, hidden behind her confident exterior. She understands people, not because she is manipulative, but because she sees through pretense and values truth above appearances. Sagittarians often walk a fine line between wisdom and recklessness, and Meimei embodies both, because she gives sage advice to Maomao one moment, then turns around and takes a risk no one else would dare. If fans are a Sagittarius, they will see themselves in her fire, her fierce independence, and her refusal to let anyone else write her story.

3 Capricorn - Ah-Duo

December 22 – January 19

Responsible, status-conscious, and born to lead, Capricorns will relate deeply with Ah-Duo, the noble consort whose poised exterior conceals years of political survival. As someone who once held the Emperor’s favor and heart, Ah-Duo understands the palace's intricate power structure, and more importantly, how to play her role with dignified precision. Capricorns are all about long-term strategy and self-control, and Ah-Duo lives these qualities daily, enduring personal sorrow while maintaining the composure expected of her rank.

Capricorns will see a kindred spirit in Ah-Duo's steady leadership, emotional resilience, and ambition tempered by wisdom.

Beneath her composed facade is a woman who has made enormous sacrifices for the sake of duty. Capricorns often carry emotional burdens silently, driven by an inner commitment to their responsibilities. Ah-Duo is no different, because she does not seek sympathy or shortcuts; instead, she moves carefully and deliberately, knowing that her every action impacts others. Her strength is not in grand gestures but in quiet endurance and purposeful decisions. Capricorns will see a kindred spirit in Ah-Duo's steady leadership, emotional resilience, and ambition tempered by wisdom.