Fans of The Apothecary Diaries may want to mark their calendars now, because July 4 is shaping up to be a major day for the future of the series. Anime Expo 2025 has officially confirmed a special for the series, and it is coming at a critical moment on the very same day the season 2 finale airs in Japan. If fans are hoping for a season 3 announcement, all signs suggest this could be the moment.

The will feature voice actors Aoi Yuki, who voices Maomao, and Asami Seto, who voices Shisui, which has fans buzzing about the significance of their appearance. Bringing together two key cast , one of whom plays a newly important character, hints that the franchise has big things to share. And fans are hoping that those big things come in some form of a season 3 announcement.

A July 4 With Big Implications for The Apothecary Diaries

Maomao and Shisui’s Voice Actors Reunite for a Major Moment

The timing of the Anime Expo could not be more deliberate. Holding a major event for The Apothecary Diaries in Los Angeles on the same day the final episode of season 2 airs feels like more than coincidence. It is likely the creators want to ride the emotional wave of the finale and capitalize on fan excitement for what is next. Whether it is a post-credits tease or a live announcement, the stars seem aligned for something major.

Aoi Yuki’s return to the U.S. convention scene is also notable. As the voice of Maomao, she is the heart of the series, and her presence makes the importance of the even deeper. Combined with Asami Seto, who plays a newer but increasingly central figure in the court's complex political web, the guest lineup may signal that season 3 could dive deeper into palace intrigue and Shisui’s role in it.

The Apothecary Diaries' Season 2’s Finale May Set the Stage

The Apothecary Diaries' Season 2’s Final Episode Could Be a Game-Changer

Season 2 has taken Maomao through increasingly dangerous corridors of court life, deepening her connection to both Jinshi and the imperial family. If the finale leaves fans with unresolved political or emotional threads, as it likely will because light novel 4 does, it would create the perfect narrative bridge into a third season. The fact that the falls on the finale’s airdate suggests producers might be planning to make an announcement immediately after the episode ends.

Anime studios often use big events like Anime Expo to make newsworthy reveals, and fans of The Apothecary Diaries are hoping this will be one of those moments. Whether it is a teaser trailer, a production confirmation, or even just a message from the staff, July 4 could bring the clarity fans have been waiting for, and maybe even some surprises no one saw coming.