Warning: This interview contains Scream spoilers

Arriving shortly after the 25th anniversary of the original film, the new Scream is finally in theaters. As a new Ghostface killer threatens Woodsboro, multiple generations of characters come together to face the threat. In keeping with the trend of legacy sequels, Scream features several franchise veterans reprising their classic roles. Among those returning faces are David Arquette and Neve Campbell, who have been with the series from the beginning.

Screen Rant spoke with the two actors about their return to the franchise, the future of the Scream series, and much more.

Screen Rant: I can't believe this is happening. I'm such a longtime fan of the franchise and the new Scream is falling right around the 25th anniversary and we're going back to Stu's house. I have to know, stepping onto that set, was there a memory that came flooding back from making the first Scream as soon as you were in Stu's house again?

Neve Campbell: Just shooting that final sequence, which took us about three weeks. Because it was a long sequence and complex and wonderful. Those actors, Matt and Skeet, and everybody involved were just so phenomenal that it really brought me straight back to that time in Santa Rosa, California, which was a very, very special time for all of us and obviously meant a lot to our lives.

There is so much great trivia. I always read all the casting stuff because there are so many different, alternate timelines of what Scream almost was. Was there ever a version where you almost played a different character within Scream?

David Arquette: Originally, they wanted me to look at some of the other characters in the film. But I told Wes, "I really love the role of Dewey. I think I could bring something different to it." And he was like, "That's very interesting." And then luckily, I got cast and it changed my life.

Is the Billy Loomis thing true? They wanted you to look at Billy?

David Arquette: It wasn't just necessarily Billy Loomis. It was just, "Look at all the younger roles," like one of the kids in high school, and I felt like I was older than them, even though I was probably close to the same age.

Neve Campbell as Sidney Prescott in Scream 2022

Well, you chose right because Dewey is one of my faves. And I am handling the Dewey/ Gale split worse than any split that's ever happened. How did you feel when you initially found out they weren't together anymore? Did you take issue with it? Did it make sense to you?

David Arquette: There were other elements that I was kind of.. that didn't feel like Dewey. But I thought it was really interesting that his life didn't work out the way he sort of expected, and I think that was an interesting place to start.

We're somewhere in sequel/reboot territory, all will be revealed. But I'm just curious as a fan, do you feel like there are more stories to be told in Woodsboro? Do you see this as the final time the legacy cast will face Ghostface? or do we not know at this point?

Neve Campbell: It would seem there are always more stories to be told in Woodsboro and there is a taste for it. So, I think, if people love this one, I would imagine there will be an appetite and we, of course, would all love to be a part of it.

David Arquette: Ghostface is such an iconic character.

I want to ask because we see Sidney jogging along, she's pushing a stroller. This is in the trailer. And then we see you wearing a ring. Do you know who Sidney marries?